Developer · Local MCP server

Rosetta MCP Server

Rosetta/PyRosetta protein modeling and Biotite translation for computational biology.

What the MCP Registry states

The entry as published to the official MCP Registry (read 2026-10-04), latest version.

Registry name
io.github.Arielbs/rosetta-mcp-server
Version
1.3.1
Status
Active
Category
developer
Transport
stdio (local process)
Package
npm
Published
2026-04-03
Updated
2026-04-03
Publisher
Arielbs (GitHub)
Repository
github.com/Arielbs/rosetta-mcp-server
Source
Registry API entry

Packages

RegistryPackageVersionTransportEnvironment variables
npmrosetta-mcp-server1.3.1stdioROSETTA_BIN, PYTHON_BIN, MCP_DEBUG

How to connect Rosetta MCP Server

Rosetta MCP Server runs locally from a Node.js package published to the npm registry: rosetta-mcp-server version 1.3.1. It speaks MCP over stdio, so the client starts it as a program and talks to it through standard input and output. It needs Node.js; clients usually start it with npx — the usual command is npx -y rosetta-mcp-server@1.3.1. It reads these environment variables: ROSETTA_BIN, PYTHON_BIN and MCP_DEBUG; set them in the client's configuration for this server.

In the mcpServers JSON format that many desktop and editor MCP clients read, the entry looks like this (placeholders in angle brackets):

{
  "mcpServers": {
    "rosetta-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "rosetta-mcp-server@1.3.1"
      ],
      "env": {
        "ROSETTA_BIN": "<value>",
        "PYTHON_BIN": "<value>",
        "MCP_DEBUG": "<value>"
      }
    }
  }
}

Derived from the registry entry, not tested here. What the server does, and on what terms, is set by its publisher; check its repository or website before giving it access to your accounts or files. How to add an MCP server to an assistant · Before you connect

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